Modification of AFM Tips for Facilitating Picking-up of Nanoparticles
WANG Peng1,3, YANG Hai-Jun1,3, WANG Hua-Bin1,3, LI Hai1, WANG Xin-Yan1,3, WANG Ying1, LÜ Jun-Hong1 , LI Bin1, ZHANG Yi1, HU Jun1,2
1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 2018002Bio-X Life Science Research Center, College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai 2002403Graduate School of the Chinese Academy of Sciences, Beijing 100049
Modification of AFM Tips for Facilitating Picking-up of Nanoparticles
WANG Peng1,3, YANG Hai-Jun1,3, WANG Hua-Bin1,3, LI Hai1, WANG Xin-Yan1,3, WANG Ying1, LÜ Jun-Hong1 , LI Bin1, ZHANG Yi1, HU Jun1,2
1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 2018002Bio-X Life Science Research Center, College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai 2002403Graduate School of the Chinese Academy of Sciences, Beijing 100049
摘要The radius of atomic force microscope (AFM) tip is a key factor that influences nonspecific interactions between AFM tip and nanoparticles. Generally, a tip with larger radius contributes to a higher efficiency of picking up nanoparticles. We provide two methods for modifying the AFM tip: one is to wear a tip apex on a solid substrate and the other is to coat a tip with poly (dimethylsiloxane) (PDMS). Both the approaches can enhance the adhesion force between the tip and nanoparticles by increasing tip radius. The experimental results show that a modified tip, compared to an unmodified one, achieves six-fold efficiency improvement in the capture of targeted colloidal gold nanoparticles.
Abstract：The radius of atomic force microscope (AFM) tip is a key factor that influences nonspecific interactions between AFM tip and nanoparticles. Generally, a tip with larger radius contributes to a higher efficiency of picking up nanoparticles. We provide two methods for modifying the AFM tip: one is to wear a tip apex on a solid substrate and the other is to coat a tip with poly (dimethylsiloxane) (PDMS). Both the approaches can enhance the adhesion force between the tip and nanoparticles by increasing tip radius. The experimental results show that a modified tip, compared to an unmodified one, achieves six-fold efficiency improvement in the capture of targeted colloidal gold nanoparticles.
WANG Peng;YANG Hai-Jun;WANG Hua-Bin;LI Hai;WANG Xin-Yan;WANG Ying;LÜJun-Hong;LI Bin;ZHANG Yi;HU Jun;. Modification of AFM Tips for Facilitating Picking-up of Nanoparticles[J]. 中国物理快报, 2008, 25(7): 2407-2409.
WANG Peng, YANG Hai-Jun, WANG Hua-Bin, LI Hai, WANG Xin-Yan, WANG Ying, LÜ, Jun-Hong, LI Bin, ZHANG Yi, HU Jun,. Modification of AFM Tips for Facilitating Picking-up of Nanoparticles. Chin. Phys. Lett., 2008, 25(7): 2407-2409.
2008, Vol. 25 
