| CROSS-DISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY |
|
|
|
|
Calculation of the Physical and Microdosimetric Parameters of Electron and Alpha-Particle Radiation Using Monte Carlo Simulations |
| GENG Jin-Peng, CAO Tian-Guang, LI Duo-Fang, AN Hai-Long, HAN Ying-Rong, LI Jin, HU Jin-Shan, LI Nan-Nan, ZHAN Yong** |
Institute of Biophysics, School of Sciences, Hebei University of Technology, Tianjin 300401
|
|
| Cite this article: |
|
GENG Jin-Peng, CAO Tian-Guang, LI Duo-Fang et al 2014 Chin. Phys. Lett. 31 038701 |
|
|
|
|
Abstract Various ionizing radiations, such as electrons and alpha particles, transfer their energy to media by produced secondary electrons and induce double- or single-strand break of DNA, which result in variable effects. To understand how the ionizing radiations interact with DNA and break it, several models have been developed, most of them consider the water as a vapor state. Actually, the ionizing particles interact with DNA which is solved in liquid water. To compare the difference of vapor and liquid water models, we calculate the stopping power, continuous slowing down approximation (CSDA) range and S value of electrons and alpha particles at cellular scale in liquid and vapor by Monte Carlo simulations, respectively. Our data show that the stopping power and CSDA range are different in liquid and vapor water in a special energy range. For many S values, the liquid model is better than the vapor model when the energy of the electrons is higher than 100 keV and the vapor model is higher than the liquid model for the 1 MeV alpha particles.
|
|
|
Received: 18 November 2013
Published: 28 February 2014
|
|
| PACS: |
87.10.Rt
|
(Monte Carlo simulations)
|
| |
23.40.-s
|
(β-decay;double β-decay; electron and muon capture)
|
| |
23.60.+e
|
(α-decay)
|
|
|
|
|
|
[1] Barth R F, Coderre J A, Vicente M G and Blue T E 2005 Clin. Cancer Res. 11 3987
[2] Geng J P, Li D F, Cao T G, Chen F Y, Hu C L, Li J, Wang X Z and Zhan Y 2012 Mol. Plant Breed. 3 132
[3] Carvajal M A, García-Pareja S, Guirado D, Vilches M, Anguiano M, Palma A J and Lallena A M 2009 Phys. Med. Biol. 54 6263
[4] Gerardy I, Rodenas J, Dycke M, Gallardo S and Tondeur F 2008 J. Phys.: Conf. Ser. 102 012012
[5] Xie Z, Zou L, Hou Q and Zheng X 2013 Acta Phys. Sin. 62 068701 (in Chinese)
[6] Jiang D J and Tan Z Y 2010 Chin. Phys. Lett. 27 033401
[7] Agostinelli S et al 2003 Nucl. Instrum. Methods Phys. Res. Sect. A 506 250
[8] Incerti S et al 2010 Int. J. Model. Simul. Sci. Comput. 1 157
[9] Tufan M C, Namdar T and Gumus H 2013 Radiat. Environ. Biophys. 52 245
[10] Zhang J H, Liu J R and Li Y 1989 Chin. Phys. Lett. 6 205
[11] Snyder W S, Ford M R, Warner G G and Watson S B 1975 MIRD Pamphlet No. 11 (New York: Society of Nuclear Medicine)
[12] Ma Y Z, Geng J P, Gao S and Bao S L 2006 Med. Phys. 33 4739 |
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
