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Monte Carlo Simulation of Kinesin Movement with a Lattice Model |
WANG Hong;DOU Shuo-Xing;WANG Peng-Ye |
Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080 |
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Cite this article: |
WANG Hong, DOU Shuo-Xing, WANG Peng-Ye 2005 Chin. Phys. Lett. 22 2980-2982 |
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Abstract Kinesin is a processive double-headed molecular motor that moves along a microtubule by taking about 8nm steps. It generally hydrolyzes one ATP molecule for taking each forward step. The processive movement of the kinesin molecular motors is numerically simulated with a lattice model. The motors are considered as Brownian particles and the ATPase processes of both heads are taken into account. The Monte Carlo simulation results agree well with recent experimental observations, especially on the relation of velocity versus ATP and ADP concentrations.
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Keywords:
87.16.Nn
87.16.Ac
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Published: 01 November 2005
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