Original Articles |
|
|
|
|
Observation of Hydration--Drying Effect on Clotrimazole--Carbopol System |
M. Todica |
Faculty of Physics, Babes-Bolyai University, 400084 Cluj-Napoca, Romania |
|
Cite this article: |
M. Todica 2008 Chin. Phys. Lett. 25 2674-2676 |
|
|
Abstract The possibility to use the polyacrylic acid (carbopol) as polymeric matrix for the clotrimazole is analysed. The hydration--drying effect on the polymeric matrix is observed by Raman spectroscopy. Similar observations are obtained on the clotrimazole included in the polymeric matrix. No modifications of the properties of the clotrimazole and of the polymeric matrix are observed under the repeated action of water.
|
Keywords:
82.70.Dd
82.70.Gg
82.70.Kj
|
|
Received: 15 March 2008
Published: 26 June 2008
|
|
|
|
|
|
[1] Hoffman A S 2002 Adv. Drug Del. Rev. 43 3 [2] Venkatesh S, Sizemore S P et al 2007 Biomaterials 28 717 [3] Sharma G, Jain S et al 2006 Acta Pharm. 56337 [4] Sriamornsak P and Kennedy R A 2006 Int. J. Pharm. 323 78 [5] Munasur A P and Pillay V 2006 Int. J. Pharm. 323 43 [6] Berger J, Reist M and Chenite A 2005 Int. J. Pharm. 228 197 [7] Bogquist P, Korner A et al 2006 J. ControlledRelease 113 216 [8] Nae H N and Reicher W W 1992 Rheol. Acta 31351 [9] Stuart B 2002 Polymer Analysis (New York: Wiley) [10] Rubinstein M and Colby R 2002 Polymer Physics(Oxford: Oxford University Press) [11] Yoon S, Ichikawa K, MacKnight W J and Hsu S L 1995 Macromolecules 28 5063 [12] Yoon S, MacKnight W J and Hsu S L 1997 J. Appl.Polym. Sci. 21 197 [13] Umemura J and Hayashi S 1974 Bull. Inst. Chem. Res.Kyoto Univ. 52 585 [14] Itoh K, Yaita M, Hasegawa T, Fujii S and Misson Y 1990 J. Electron Spectrosc. Relat. Phenomena 54/55 923 [15] Islam M T, Rodriguez-Homedo N, Ciotti S and Ackermann C2004 AAPS J. 6 article 35 [16] Goodrich B F 1997 Polymers for PharmaceuticalApplications I: General Overview (Cleveland, OH:Goodrich Chemicals) [17] Kemper M S, Magnuson E J, Lowry S R et al 2001 AAPSPharm. Sci. 3 E23 |
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|