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Coupling Effect of Ion Channel Clusters on Calcium Signalling |
| TANG Jun1,2;JIA Ya1;YI Ming1;MA Jun1;YU Guang1 |
| 1Department of Physics and Institute of Biophysics, Huazhong Normal University, Wuhan 4300792College of Science, China University of Mining and technology, Xuzhou 221008 |
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| Cite this article: |
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TANG Jun, JIA Ya, YI Ming et al 2008 Chin. Phys. Lett. 25 1149-1152 |
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Abstract Based on a modified intracellular Ca2+ model involving diffusive coupling of two calcium ion channel clusters, the effects of coupling on calcium signalling are numerically investigated. The simulation results indicate that the diffusive coupling of clusters together with internal noise determine the calcium dynamics of single cluster, and for either homogeneous or heterogeneous coupled clusters, the synchronization of clusters, which is important to calcium signalling, is enhanced by the coupling effect.
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| Keywords:
87.16.Ac
02.60.Cb
05.40.-a
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Received: 28 November 2007
Published: 27 February 2008
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| PACS: |
87.16.Ac
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02.60.Cb
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(Numerical simulation; solution of equations)
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05.40.-a
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(Fluctuation phenomena, random processes, noise, and Brownian motion)
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