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A Coarse Estimation of Cell Size Region from a Mesoscopic Stochastic Cell Cycle Model |
| YI Ming1;JIA Ya1;LIU Quan1;ZHU Chun-Lian2;YANG Li-Jian1 |
| 1Department of Physics and Institute of Biophysics, Huazhong Normal University, Wuhan 4300792Department of Physics, Jianghan University, Wuhan 430056 |
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| Cite this article: |
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YI Ming, JIA Ya, LIU Quan et al 2007 Chin. Phys. Lett. 24 1829-1832 |
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Abstract Based on a deterministic cell cycle model of fission yeast, the effects of the finite cell size on the cell cycle regulation in wee1- cdc25△ double mutant type are numerically studied by using of the chemical Langevin equations. It is found that at a certain region of cell size, our numerical results from the chemical Langevin equations are in good qualitative agreement with the
experimental observations. The two resettings to the G2 phase from early stages of mitosis can be induced under the moderate cell size. The quantized cycle times can be observed during such a cell size region. Therefore, a coarse estimation of cell size is obtained from the mesoscopic stochastic cell cycle model.
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05.40.-a
87.17.Aa
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Received: 05 March 2007
Published: 25 June 2007
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| PACS: |
05.40.-a
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(Fluctuation phenomena, random processes, noise, and Brownian motion)
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87.17.Aa
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(Modeling, computer simulation of cell processes)
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