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Two-Dimensional Photoacoustic Imaging of Blood Vessel Networks within Biological Tissues |
SU Yi-Xiong1;Ruikang K. WANG2;ZHANG Fan1;YAO Jian-Quan1 |
1Institute of Lasers and Optoelectronics, College of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072
2Department of Biomedical Engineering, OGI School of Science and Engineering, Oregon Health $\&$ Science University, OR97006, USA |
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Cite this article: |
SU Yi-Xiong, Ruikang K. WANG, ZHANG Fan et al 2006 Chin. Phys. Lett. 23 512-515 |
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Abstract Photoacoustic tomography (PAT) is a powerful imaging technique for medical diagnosis because it combines the merits and most compelling features of light and sound. We describe a PAT experimental system constructed in our laboratory which consists of a Q-switched Nd:YAG pulse laser operating at 532nm with a 8-ns pulse width to generate the photoacoustic signals from a biological sample. Two-dimensional photoacoustic imaging of blood vessel networks 1cm below the tissue surface is achieved. We also successfully demonstrate that the system is capable of imaging the blood vessels over the ex vivo rat brain with skull and skin intact.
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Keywords:
87.57.Ce
43.35.+d
43.60.+d
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Published: 01 February 2006
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PACS: |
87.57.Ce
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43.35.+d
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(Ultrasonics, quantum acoustics, and physical effects of sound)
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43.60.+d
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(Acoustic signal processing)
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