Original Articles |
|
|
|
|
Dynamical Properties of Potassium Ion Channels with a Hierarchical Model |
ZHAN Yong;AN Hai-Long;YU Hui;ZHANG Su-Hua;HAN Ying-Rong |
School of Sciences, Hebei University of Technology, Tianjin 300130 |
|
Cite this article: |
ZHAN Yong, AN Hai-Long, YU Hui et al 2006 Chin. Phys. Lett. 23 2906-2908 |
|
|
Abstract It is well known that potassium ion channels have higher permeability than K ions, and the permeable rate of a single K ion channel is about 108 ions per second. We develop a hierarchical model of potassium ion channel permeation involving ab initio quantum calculations and Brownian dynamics simulations, which can consistently explain a range of channel dynamics. The results show that the average velocity of K ions, the mean permeable time of K ions and the permeable rate of single channel are about 0.92nm/ns, 4.35ns and 2.30× 108ions/s, respectively.
|
Keywords:
05.10.Gg
31.15.Ew
87.16.Uv
|
|
Published: 01 November 2006
|
|
|
|
|
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|