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Displacement and Force Measurements with Quadrant Photodetector in Optical Tweezers |
| GUO Hong-Lian1;LIU Chun-Xiang1;LI Zhao-Lin1;DUAN Jian-Fa2;HAN Xue-Hai2;CHENG Bing-Ying1;ZHANG Dao-Zhong1 |
| 1Optical Physics Laboratory, Institute of Physics and Center for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100080
2State Key Laboratory of Biomacromolecles, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101
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| Cite this article: |
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GUO Hong-Lian, LIU Chun-Xiang, LI Zhao-Lin et al 2003 Chin. Phys. Lett. 20 950-952 |
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Abstract A technique of displacement and force measurements with a photodiode quadrant detector in an optical tweezers system is presented. The stiffness of optical trap is calibrated and the leukemia cell membrane tension is measured. The results show that the optical tweezers combined with the quadrant detector is a very useful tool for detecting the displacement and force with a millisecond-order response.
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| Keywords:
81.70.Fy
87.15.La
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Published: 01 June 2003
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| PACS: |
81.70.Fy
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(Nondestructive testing: optical methods)
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87.15.La
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(Mechanical properties)
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