| FUNDAMENTAL AREAS OF PHENOMENOLOGY(INCLUDING APPLICATIONS) |
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Label-Free Microscopic Imaging Based on the Random Matrix Theory in Wavefront Shaping |
| Li-Qi Yu1, Xin-Yu Xu1, Zhen-Feng Zhang1, Qi Feng1, Bin Zhang2, Ying-Chun Ding1**, Qiang Liu2** |
1College of Mathematics and Physics, Beijing University of Chemical Technology, Beijing 100029
2State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing 100084
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| Cite this article: |
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Li-Qi Yu, Xin-Yu Xu, Zhen-Feng Zhang et al 2019 Chin. Phys. Lett. 36 114203 |
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Abstract Wavefront shaping technology has mainly been applied to microscopic fluorescence imaging through turbid media, with the advantages of high resolution and imaging depth beyond the ballistic regime. However, fluorescence needs to be introduced extrinsically and the field of view is limited by memory effects. Here we propose a new method for microscopic imaging light transmission through turbid media, which has the advantages of label-free and discretional field of view size, based on transmission-matrix-based wavefront shaping and the random matrix theory. We also verify that a target of absorber behind the strong scattering media can be imaged with high resolution in the experiment. Our method opens a new avenue for the research and application of wavefront shaping.
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Received: 23 August 2019
Published: 21 October 2019
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| Fund: Supported by the National Key Research and Development Program of China under Grant No 2017YFB1104500, the Beijing Natural Science Foundation under Grant No 7182091, the National Natural Science Foundation of China under Grant No 21627813, and the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital under Grant No PYBZ1801. |
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