Chin. Phys. Lett.  2012, Vol. 29 Issue (9): 097803    DOI: 10.1088/0256-307X/29/9/097803
CONDENSED MATTER: ELECTRONIC STRUCTURE, ELECTRICAL, MAGNETIC, AND OPTICAL PROPERTIES |
Preparation and Characterization of Bimodal Magnetofluorescent Nanoprobes for Biomedical Application
LEI Jie-Mei1, XU Xiao-Liang1**, LIU Ling1, YIN Nai-Qiang1, ZHU Li-Xin2**
1Department of Physics, University of Science and Technology of China, Hefei 230026
2Center Laboratory, First Affiliated Hospital, Anhui Medical University, Hefei 230022
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LEI Jie-Mei, XU Xiao-Liang, LIU Ling et al  2012 Chin. Phys. Lett. 29 097803
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Abstract Magnetic-fluorescent bifunctional Fe3O4/SiO2-CdTeS nanocomposites are synthesized. Fe3O4 superparamagnetic nanoparticles are firstly prepared through the thermal decomposition of Fe oleate precursors and coated with a mesoporous silica shell using the St?ber method, and the silica surface is then modified with positively charged amino groups by adding 3-aminopropyltrimethoxysilane. Finally, negatively charged CdTeS quantum dots are linked and assembled onto the positively charged surface of Fe3O4/SiO2 through electrostatic interactions. X-ray diffraction, transmission electron microscopy, photoluminescence spectroscopy, and magnetometry are applied to characterize the nanocomposites. The results show that the bifunctional nanocomposites combine the optical properties of near-infrared CdTeS quantum dots with the superparamagnetic properties of Fe3O4 perfectly, expressing the potential application as a biocompatible magnetofuorescent nanoprobe for in vivo labelling.
Received: 18 June 2012      Published: 01 October 2012
PACS:  78.30.Fs (III-V and II-VI semiconductors)  
  75.70.Cn (Magnetic properties of interfaces (multilayers, superlattices, heterostructures))  
  87.64.kv (Fluorescence)  
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https://cpl.iphy.ac.cn/10.1088/0256-307X/29/9/097803       OR      https://cpl.iphy.ac.cn/Y2012/V29/I9/097803
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LEI Jie-Mei
XU Xiao-Liang
LIU Ling
YIN Nai-Qiang
ZHU Li-Xin
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