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Image Restoration Phase-Filtering Lateral Superresolution Confocal Microscopy |
| ZHAO Wei-Qian;QIU Li-Rong;CHEN Shan-Shan;FENG Zheng-De |
| Department of Automation Measurement and Control Engineering, Harbin Institute of Technology, Harbin 150001 |
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| Cite this article: |
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ZHAO Wei-Qian, QIU Li-Rong, CHEN Shan-Shan et al 2006 Chin. Phys. Lett. 23 856-859 |
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Abstract Image restoration phase-filtering lateral superresolution confocal microscopy, a new approach, is proposed to achieve lateral superresolution using a confocal microscope. This approach uses a lateral superresolution pupil filter to preliminarily improve its lateral resolution and uses a single-image superresolution restoration technique based on a maximum likelihood estimate to further improve its lateral resolution. The new approach has the advantages of a low cost and the remarkable superresolution effect without excessive system complexity. Experiments indicate that the proposed approach can improve the lateral resolution of a confocal microscope from 0.3μm to less than 0.1μm when λ=632.8nm and NA=0.85.
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| Keywords:
42.79.Ci
42.25.Fx
42.30.Lr
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Published: 01 April 2006
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| PACS: |
42.79.Ci
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(Filters, zone plates, and polarizers)
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42.25.Fx
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(Diffraction and scattering)
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42.30.Lr
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(Modulation and optical transfer functions)
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