Conservation of Hydrophobic and Hydrophilic Residues in Four-Helix Bundle

Chin. Phys. Lett.

2003, Vol. 20

Issue (10): 1883-1886 DOI:

Original Articles

Conservation of Hydrophobic and Hydrophilic Residues in Four-Helix Bundle

QIN Meng;WANG Jun;WANG Wei

National Laboratory of Solid State Microstructure, Nanjing University, Nanjing 210093

Cite this article:

QIN Meng, WANG Jun, WANG Wei 2003 Chin. Phys. Lett. 20 1883-1886

Download: PDF(440KB)
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks

Abstract The conservation of the hydrophobic and the hydrophilic residue sites obtained from 1000 designed sequences with the Z-score method for a four-helix bundle has been studied. The folding dynamic and thermodynamic features of the designed sequences and their different mutations are also studied. It is found that this conservation is related to the stability and the fast folding of the model proteins. Our results are consistent with the experimental results.

Keywords: 87.15.Cc 87.15.Aa 87.14.Ee

Published: 01 October 2003

PACS:	87.15.Cc	(Folding: thermodynamics, statistical mechanics, models, and pathways)
	87.15.Aa
	87.14.Ee

TRENDMD:

URL:

https://cpl.iphy.ac.cn/ OR https://cpl.iphy.ac.cn/Y2003/V20/I10/01883

Service
	E-mail this article
	E-mail Alert
	RSS
Articles by authors
	QIN Meng
	WANG Jun
	WANG Wei

Related articles from Frontiers Journals

[1]	XU Wei-Xin, LI Yang, ZHANG John Z. H.. Calculation of Collective Variable-based PMF by Combining WHAM with Umbrella Sampling[J]. Chin. Phys. Lett., 2012, 29(6): 1883-1886
[2]	SUN Li, WANG Jun, WANG Wei. Dissection of the Zipping-and-Assembly Mechanism for Folding of Model Proteins[J]. Chin. Phys. Lett., 2010, 27(3): 1883-1886
[3]	CHEN Hua, CHEN Gui-Ying, LI Shu-Qin, WANG Li. Reversible Conformational Changes of PsbO Protein Detected by Terahertz Time-Domain Spectroscopy[J]. Chin. Phys. Lett., 2009, 26(8): 1883-1886
[4]	Waqar Ahmad. Co-Adsorption of CO in NO-CO Reaction on a Metal Catalytic Surface Studied by Computer Simulation[J]. Chin. Phys. Lett., 2009, 26(3): 1883-1886
[5]	XU Feng-Dan, LIU Zeng-Rong, ZHANG Zhi-Yong, SHEN Jian-Wei,. Robust and Adaptive MicroRNA-Mediated Incoherent Feedforward Motifs[J]. Chin. Phys. Lett., 2009, 26(2): 1883-1886
[6]	M. Khalid, A. U. Qaisrani, M. G. Ullah. Transient Non-Thermal Mobility of CO for CO--NO Catalytic Reaction on Square Lattice: Monte Carlo Simulation[J]. Chin. Phys. Lett., 2008, 25(4): 1883-1886
[7]	Waqar Ahmad. NO--CO--O₂ Reaction on a Metal Catalytic Surface using Eley--Rideal Mechanism[J]. Chin. Phys. Lett., 2008, 25(10): 1883-1886
[8]	XU Chun-Hua, GUO Hong-Lian, QU E, LI Zhao-Lin, YUAN Ming, CHENGBing-Ying, ZHANG Dao-Zhong. Measurement of Binding Force between Microtubule-Associated Protein and Microtubule[J]. Chin. Phys. Lett., 2007, 24(9): 1883-1886
[9]	ZUO Guang-Hong, HU Jun, FANG Hai-Ping,. Protein Folding under Mediation of Ordering Water: an Off-Lattice Go^--Like Model Study[J]. Chin. Phys. Lett., 2007, 24(8): 1883-1886
[10]	CHEN Hua, QU Yuan-Gang, PENG Wei-Xian, KUANG Ting-Yun, LI Liang-Bi, WANG Li. Investigation of Chlorophyll Protein 43 and 47 Denaturation by Terahertz Time-Domain Spectroscopy[J]. Chin. Phys. Lett., 2007, 24(7): 1883-1886
[11]	LIU Hong-Rong, YANG Qi-Bin, CHENG Ling-Peng, ZENG Song-Jun, CAI Can-Ying. Three-Dimensional Reconstruction of Icosahedral Virus by Symmetry-Adapted Functions[J]. Chin. Phys. Lett., 2007, 24(6): 1883-1886
[12]	YAN Shi-Wei, , WANG Qi, XIE Bai-Song, ZHANG Feng-Shou,. Oscillatory Activities in Regulatory Biological Networks and Hopf Bifurcation[J]. Chin. Phys. Lett., 2007, 24(6): 1883-1886
[13]	WU Heng-An, LONG Rong, WANG Xiu-Xi, WANG Feng-Chao. Elastic Interaction between a String of Cells and an Individual Cell[J]. Chin. Phys. Lett., 2007, 24(5): 1883-1886
[14]	WU Heng-An, WANG Xiu-Xi, YAN Shun-Ping. Active Control of Cellular Orientation through In-Situ Stress in the Substrate[J]. Chin. Phys. Lett., 2007, 24(12): 1883-1886
[15]	Waqar Ahmad, Musa Kaleem Baloach. Monte Carlo Study of CO--NO Catalytic Surface Reaction Including CO--CO Repulsion[J]. Chin. Phys. Lett., 2006, 23(4): 1883-1886

Viewed

Full text

Abstract