摘要We establish a new model for ionic waves along microtubules based on polyelectrolyte features of cylindrical biopolymers. The nonlinear transmission line described by a nonlinear differential equation is obtained with stable kink solution pertinent to the shape of the front of accompanying potential. The localized ionic wave could be used to explain the behavior of microtubules as biomolecular transistors capable of amplifying electrical information in neurons.
Abstract:We establish a new model for ionic waves along microtubules based on polyelectrolyte features of cylindrical biopolymers. The nonlinear transmission line described by a nonlinear differential equation is obtained with stable kink solution pertinent to the shape of the front of accompanying potential. The localized ionic wave could be used to explain the behavior of microtubules as biomolecular transistors capable of amplifying electrical information in neurons.
ILIC D. I.;SATARIC M. V.;RALEVIC N.. Microtubule as a Transmission Line for Ionic Currents[J]. 中国物理快报, 2009, 26(7): 73101-073101.
ILIC D. I., SATARIC M. V., RALEVIC N.. Microtubule as a Transmission Line for Ionic Currents. Chin. Phys. Lett., 2009, 26(7): 73101-073101.
[1]Sataric M V and Tuszynski J A 2003 Phys. Rev. E 67 011901 [2] Sataric M V, Budinski-Petkovic L and Lon\v{crevic I2007 Int. J. Mod. Phys. B 32 5387 [3] Manning G 1969 J. Chem. Phys. 51 924 [4] Tuszynski J A, Portet S, Dixon J M, Luxford C andCantiello H F 2004 Biophys. J. 86 1890 [5] Sataric M V, Ilic D I, Ralevic N, Tuszynski J A 2009 Eur. Biophys. J. (accepted) [6] Minoura I and Muto E 2006 Biophys. J. 90 3739 [7] Wang K, Jan Rappel W and Levine H 2004 Phys. Biol. 1 27 [8] Priel A, Ramos A J, Tuszynski J A and Cantiello H F 2006 Biophys. J. 90 4639