It is well known that potassium ion channels have higher permeability than K ions, and the permeable rate of a single K ion channel is about 108 ions per second. We develop a hierarchical model of potassium ion channel permeation involving ab initio quantum calculations and Brownian dynamics simulations, which can consistently explain a range of channel dynamics. The results show that the average velocity of K ions, the mean permeable time of K ions and the permeable rate of single channel are about 0.92nm/ns, 4.35ns and 2.30× 108ions/s, respectively.
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ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong. Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J]. Chin. Phys. Lett., 2006, 23(11): 2906-2908.
ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong. Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J]. Chin. Phys. Lett., 2006, 23(11): 2906-2908.
ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong. Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J]. Chin. Phys. Lett., 2006, 23(11): 2906-2908.
ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong. Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J]. Chin. Phys. Lett., 2006, 23(11): 2906-2908.
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