What Governs the Unzipping Process of Double-Stranded DNA

The unzipping process of double-stranded DNA is analysed using a discrete model at the base level Chin. Phys. Lett. 22(2005)1540. The numerical results are consistent with the experimental observations on the force-displacement behaviour including the sequence-dependence. We find that the hydrogen bond interaction in a base pair is crucially important to the force--displacement profile.