| CROSS-DISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY |
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Photon-Measurement Density Function of Fluorescence Molecular Tomography Based on Direct Method |
| QUAN Guo-Tao, GONG Hui, FU Jian-Wei, DENG Yong**
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Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074
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| Cite this article: |
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QUAN Guo-Tao, GONG Hui, FU Jian-Wei et al 2010 Chin. Phys. Lett. 27 118701 |
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Abstract Photon-measurement density function (PMDF), which is the kernel of fluorescence molecular tomography (FMT), largely determines the accuracy of reconstruction result of FMT. Based on the direct method, we propose an expression of PMDF in FMT, which is derived from the finite element method (FEM) solution of the diffusion equation. Compared with the traditional expression based on the perturbation method, the accuracy of expression based on the direct method is shown in theory. Lastly the reconstruction results of phantoms prove this accuracy in experiment.
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| Keywords:
87.57.Q-
42.30.Wb
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Received: 30 March 2010
Published: 22 October 2010
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| PACS: |
87.57.Q-
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(Computed tomography)
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42.30.Wb
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(Image reconstruction; tomography)
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[1] Ntziachristos V 2006 Annu. Rev. Biomed. Eng. 8 1
[2] Xiang L Z, Xing D, Gu H M, Zhou F F et al 2007 Chin. Phys. Lett. 24 751
[3] Su Y X, Wang R K K, Zhang F and Yao J Q 2006 Chin. Phys. Lett. 23 512
[4] Graves E E, Ripoll J, Weissleder R and Ntziachristos V 2003 Med. Phys. 30 901
[5] Zhang L, Gao F, He H, and Zhao H 2008 Opt. Express 16 7214
[6] Song X, Wang D, Chen N, Bai J et al 2007 Opt. Express 15 18300
[7] Arridge S R 1995 Appl. Opt. 34 7395
[8] Arridge S R and Schweiger M 1995 Appl. Opt. 34 8026
[9] Milstein A B, Oh S, Webb K J, Bouman C A et al 2003 Appl. Opt. 42 3081
[10] Scott D, Dehghani H, Wang J, Jiang S et al 2007 Opt. Express 15 4066
[11] Boas D 1997 Opt. Express 1 404
[12] Cong A X and Wang G 2005 Opt. Express 13 9847
[13] Wang D, Liu X, Chen Y and Bai J 2009 IEEE Trans. Inf. Technol. Biomed. 13 766
[14] Gao F, Zhao H, Tanikawa Y and Yamada Y 2006 Opt. Express 14 7109
[15] Flock S T, Jacques S L, Wilson B C, Star W M et al 1992 Lasers Surg. Med. 12 510
[16] Yang X, Gong H, Quan G, Deng Y et al 2010 Rev. Sci. Instrum. 81 054304
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