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Detection Limit of Glucose Concentration with Near-InfraredAbsorption and Scattering Spectroscopy |
| LUO Yun-Han;HUANG Fu-Rong;LI Shi-Ping;CHEN Zhe |
| Department of Optoelectronic Engineering, College of Science and Technology, Jinan University, Guangzhou 510632 |
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| Cite this article: |
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LUO Yun-Han, HUANG Fu-Rong, LI Shi-Ping et al 2008 Chin. Phys. Lett. 25 1117-1119 |
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Abstract Theoretical analyses and Monte Carlo simulation are performed to investigate the detection limit of glucose concentration with near-infrared spectroscopy. The relation between detection limitation of glucose concentration and
source--detector separation is derived. Monte Carlo simulation performed with a skin-layered model shows that the ratio of effective photons from the target layer could excess 50% by selecting proper source--detector separation, and that the detection limit of glucose concentration approaches to 0.28mM, which satisfies the requirement of food and drug administration for noninvasive glucose sensing.
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| Keywords:
78.20.Ci
78.30.-j
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Received: 19 November 2007
Published: 27 February 2008
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| PACS: |
78.20.Ci
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(Optical constants (including refractive index, complex dielectric constant, absorption, reflection and transmission coefficients, emissivity))
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78.30.-j
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(Infrared and Raman spectra)
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