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Cytoplasmic Ca2+ Dynamics under the Interplay between the Different IP3R Gating Models and the Plasma Membrane Ca2+ Influx |
| CHEN Xiao-Fang, LI Cong-Xin, WANG Peng-Ye, WANG Wei-Chi |
| Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 |
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CHEN Xiao-Fang, LI Cong-Xin, WANG Peng-Ye et al 2010 Chin. Phys. Lett. 27 010504 |
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Abstract The cytoplasmic Ca2+ oscillations are investigated under the effect of CRAC channels in non-excitable cells (especially in T cells). The oscillatory Ca2+ signals can be modulated as the amplitude-, frequency- and mixed amplitude-frequency modulation modes dependent on the different IP3R gating models. Bifurcation analyses show that Ca2+ signals in the single positive feedback loop model is a mixed modulation mode. In contrast, Ca2+ signals in the Mak-McBride-Foskett model demonstrates approximately the frequency modulation mode only with slight amplitude shifts.
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05.45.-a
82.40.Bj
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Received: 02 July 2009
Published: 30 December 2009
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| PACS: |
05.45.-a
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(Nonlinear dynamics and chaos)
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82.40.Bj
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(Oscillations, chaos, and bifurcations)
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