Chin. Phys. Lett.  2007, Vol. 24 Issue (9): 2692-2695    DOI:
Original Articles |
Humidity Effects on Imaging and Nanomanipulation of Individual DNA Molecules on HOPG Surface
ZHOU Xing-Fei1;ZHANG Yi2;WANG Hua-Bin2;NIU Dong-Xiao2;WANG
Pei-Qing1;HU Jun2,3
1Department of Physics, College of Sciences, Ningbo University, Ningbo 3152112Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 2018003Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai 200240
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ZHOU Xing-Fei, ZHANG Yi, WANG Hua-Bin et al  2007 Chin. Phys. Lett. 24 2692-2695
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Abstract Single DNA molecules are aligned on highly ordered pyrolytic graphite (HOPG) surface in ambient air. It is shown that environmental humidity has a remarkable influence on the measured height of DNA by atomic force microscopy (AFM), probably due to the conformation transition of DNA. We also demonstrate that DNA molecules deposited on HOPG surfacecan be `pushed' much more easily by AFM tip at high humidity than at low one.
Keywords: 81.65.Cf      87.64.Dz      87.15.La     
Received: 28 April 2007      Published: 16 August 2007
PACS:  81.65.Cf (Surface cleaning, etching, patterning)  
  87.64.Dz (Scanning tunneling and atomic force microscopy)  
  87.15.La (Mechanical properties)  
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https://cpl.iphy.ac.cn/       OR      https://cpl.iphy.ac.cn/Y2007/V24/I9/02692
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ZHOU Xing-Fei
ZHANG Yi
WANG Hua-Bin
NIU Dong-Xiao
WANGPei-Qing
HU Jun
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