| Original Articles |
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Synchronized Anti-Phase and In-Phase Oscillations of Intracellular Calcium Ions in Two Coupled Hepatocytes System |
| SHEN Chuan-Sheng1,2;CHEN Han-Shuang2;ZHANG Ji-Qian2 |
| 1Department of Educational Technology, Anqing Teachers College, Anqing 2460112College of Physics and Electronic Information, Anhui Normal University, Wuhu 241000 |
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| Cite this article: |
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SHEN Chuan-Sheng, CHEN Han-Shuang, ZHANG Ji-Qian 2008 Chin. Phys. Lett. 25 870-873 |
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Abstract We study the dynamic behaviour of two intracellular calcium oscillators that are coupled through gap junctions both to Ca2+ and inositol(1,4,5)-trisphosphate (IP3). It is found that synchronized anti-phase and in-phase
oscillations of cytoplasmic calcium coexist in parameters space. Especially, synchronized anti-phase oscillations only occur near the onset of a Hopf bifurcation point when the velocity of IP3 synthesis is increased. In addition, two kinds of coupling effects, i.e., the diffusions of Ca2+ and IP3 among cells on synchronous behaviour, are considered. We find that small coupling of
Ca2+ and large coupling of IP3 facilitate the emergence of synchronized anti-phase oscillations. However, the result is contrary for the synchronized in-phase case. Our findings may provide a qualitative understanding about the mechanism of synchronous behaviour of intercellular calcium signalling.
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| Keywords:
05.45.Xt
05.45.-a
05.40.-a
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Received: 10 November 2007
Published: 27 February 2008
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| PACS: |
05.45.Xt
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(Synchronization; coupled oscillators)
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05.45.-a
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(Nonlinear dynamics and chaos)
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05.40.-a
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(Fluctuation phenomena, random processes, noise, and Brownian motion)
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