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An Intracellular Calcium Oscillation Model and its Property
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| YING Yang-Jun1;LI Wei-Hua2 |
| 1Laboratory of Computation Physics, Institute of Applied Physics and Computational Mathematics, PO Box 8009, Beijing 100088
2Department of Modern Education Technology, Beijing College of Education, Beijing 100035 |
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| Cite this article: |
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YING Yang-Jun, LI Wei-Hua 2003 Chin. Phys. Lett. 20 1168-1171 |
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Abstract Intracellular Ca2+ concentration oscillation is one of the typical nonlinear dynamical phenomena in biophysics. According to the experimental facts that when stimulated by different agonists, the cytosolic Ca2+ oscillations of hepatocytes show nearly constant amplitude for two different oscillation-form, simple spikes and complex bursts, we build a new 4-variables model based on the two models proposed by Hoefer [ Biophys J. 77 (1999) 1244] and Kummer et al. [ Biophys. J. 79 (2000) 1188] Our model can simulate both simple-spike and multi-spike-burst oscillations with amplitude of 0.5-0.7μmol/L in a rather wide range of parameters.
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| Keywords:
87.16.Ac
87.16.Xa
05.45.-a
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Published: 01 July 2003
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