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What Governs the Unzipping Process of Double-Stranded DNA |
WANG Xiao-Feng1,2;LEI Xiao-Ling1;FANG Hai-Ping1 |
1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800
2Graduate School of the Chinese Academy of Sciences, Beijing 100049 |
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Cite this article: |
WANG Xiao-Feng, LEI Xiao-Ling, FANG Hai-Ping 2006 Chin. Phys. Lett. 23 1339-1342 |
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Abstract The unzipping process of double-stranded DNA is analysed using a discrete model at the base level [Chin. Phys. Lett. 22(2005)1540]. The numerical results are consistent with the experimental observations on the force-displacement behaviour including the sequence-dependence. We find that the hydrogen bond interaction in a base pair is crucially important to the force--displacement profile.
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Keywords:
87.14.Gg
87.15.He
36.20.Ey
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Published: 01 May 2006
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