1The Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071 2State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071
Abstract:We study the feasibility and safety of human lung hyperpolarized (HP) $^{129}$Xe magnetic resonance imaging (MRI). There is no significant change in physiological parameters before and after the examinations of all subjects. Compared with computed tomography, HP $^{129}$Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP $^{129}$Xe MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP $^{129}$Xe MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.
Saruya S, Yamashiro T, Matsuoka S, Matsushita S, Yagihashi K and Nakajima Y 2017 Lung.195 179
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Kirby M, Svenningsen S, Owrangi A, Wheatley A, Farag A, Ouriadov A, Santyr G E, Etemad-Rezai R, Coxson H O, McCormack D G and Parraga G 2012 Radiology265 600
Driehuys B, Martinez-Jimenez S, Clevel, Z I, Metz G M, Beaver D M, Nouls J C, Kaushik S S, Firszt R, Willis C, Kelly K T, Wolber J, Kraft M and McAdams H P 2012 Radiology262 279