Quantitative Thermoacoustic Tomography for ex vivo Imaging Conductivity of Breast Tissue
HUANG Lin1, RONG Jian1, YAO Lei2, QI Wei-Zhi1, WU Dan1, XU Jin-Yu1, JIANG Hua-Bei1,2**
1School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu 610054 2J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida, U.S.A.
Abstract：We assess the feasibility of our developed quantitative thermoacoustic tomography (qTAT) system for breast tumor characterization using mastectomy specimens before the clinical investigation. A circular scanning TAT system coupled with a finite-element based reconstruction algorithm is used to recover the dielectric property distribution of normal and tumor tissues from three female subjects who underwent mastectomy. Statistical method is used to analyze the tissue dielectric properties obtained. The recovered qTAT images reveal large contrast in conductivity between tumor and normal breast tissues. In addition, significant difference in conductivity exists among all the specimens examined. Finally, the recovered tumor size for these specimens agrees well with their exact size. This preclinical evaluation suggests that it is feasible to detect and characterize a breast tumor quantitatively with our qTAT method.
. [J]. 中国物理快报, 2013, 30(12): 124301-124301.
HUANG Lin, RONG Jian, YAO Lei, QI Wei-Zhi, WU Dan, XU Jin-Yu, JIANG Hua-Bei. Quantitative Thermoacoustic Tomography for ex vivo Imaging Conductivity of Breast Tissue. Chin. Phys. Lett., 2013, 30(12): 124301-124301.
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