Enhanced Response to Subthreshold Signals by Phase Noise in a Hodgkin–Huxley Neuron
KANG Xiao-Sha, LIANG Xiao-Ming, LÜ Hua-Ping**
School of Physics and Electronic Engineering, Jiangsu Normal University, Xuzhou 221116
Abstract ：Noise has been revealed as an important cue for understanding the extraordinary ability of sensory neurons to detect or amplify external weak signals. We demonstrate that phase noise originating from the time-varying signal phase can enable an excitable neuron to excite spikes upon a periodic signal even though the signal amplitude is subthreshold. In addition, we find that there exists an optimal value on the phase noise at which the neuron's response to the subthreshold periodic signal can be significantly improved, resulting in a resonance-like behavior. Since phase noise makes the external signal aperiodic, our findings show that sensory neurons might evolve with a better performance on detecting aperiodic signals than periodic signals.
收稿日期: 2012-08-27
出版日期: 2013-03-04
:
87.19.lc
(Noise in the nervous system)
05.45.Xt
(Synchronization; coupled oscillators)
[1] Jung P and H?nggi P 1989 Europhys. Lett. 8 505 1996 Phys. Rev. Lett. 76 4074 2004 Phys. Rep. 392 321 2012 Eur. Phys. J. B 85 219 1998 Phys. Rev. Lett. 81 4012 2007 Rev. Mod. Phys. 79 829 2007 Chin. Phys. Lett. 24 2759 Acta Phys. Sin. 60 108701 (in Chinese)2008 Chin. Phys. Lett. 25 409 1993 Nature 365 337 1997 Phys. Rev. Lett. 78 1186 1998 Rev. Mod. Phys. 70 223 2000 Phys. Rev. Lett. 84 4773 2009 Phys. Rev. E 80 026206 2004 Chaos Solitons Fractals 21 177 2004 Chin. Phys. B 13 1396 2011 Int. J. Mod. Phys. B 25 3977 2011 Chin. Phys. Lett. 28 090507 2001 Chaos Solitons Fractals 12 527 2000 IEEE Trans. Circuits Syst. 47 655 Acta Phys. Sin. 60 084203 (in Chinese)2000 Phys. Rev. E 61 940 1999 Neural Comput. 11 1 2006 Sci. Am. 16 28 2011 Phys. Rev. E 84 031916 2001 Nature 410 686 1991 J. Comput. Physiol. A 169 117 2005 J. Neurosci. 25 11424 J. Physiol. 117 5001991 Phys. Rev. A 44 8032 1998 Phys. Rev. E 58 2952 2001 Phys. Rev. Lett. 88 010601 2001 Phys. Lett. A 282 23 2003 Phys. Rev. E 68 026214 1997 Phys. Rev. Lett. 78 775 1994 Phys. Rev. Lett. 72 2125 1995 Europhys. Lett. 29 191
[1]
.
[2]
.
2013, Vol. 30 
