Photon-Measurement Density Function of Fluorescence Molecular Tomography Based on Direct Method
QUAN Guo-Tao, GONG Hui, FU Jian-Wei, DENG Yong**
Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074
Photon-Measurement Density Function of Fluorescence Molecular Tomography Based on Direct Method
QUAN Guo-Tao, GONG Hui, FU Jian-Wei, DENG Yong**
Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074
摘要Photon-measurement density function (PMDF), which is the kernel of fluorescence molecular tomography (FMT), largely determines the accuracy of reconstruction result of FMT. Based on the direct method, we propose an expression of PMDF in FMT, which is derived from the finite element method (FEM) solution of the diffusion equation. Compared with the traditional expression based on the perturbation method, the accuracy of expression based on the direct method is shown in theory. Lastly the reconstruction results of phantoms prove this accuracy in experiment.
Abstract：Photon-measurement density function (PMDF), which is the kernel of fluorescence molecular tomography (FMT), largely determines the accuracy of reconstruction result of FMT. Based on the direct method, we propose an expression of PMDF in FMT, which is derived from the finite element method (FEM) solution of the diffusion equation. Compared with the traditional expression based on the perturbation method, the accuracy of expression based on the direct method is shown in theory. Lastly the reconstruction results of phantoms prove this accuracy in experiment.
QUAN Guo-Tao;GONG Hui;FU Jian-Wei;DENG Yong**
. Photon-Measurement Density Function of Fluorescence Molecular Tomography Based on Direct Method[J]. 中国物理快报, 2010, 27(11): 118701-118701.
QUAN Guo-Tao, GONG Hui, FU Jian-Wei, DENG Yong**
. Photon-Measurement Density Function of Fluorescence Molecular Tomography Based on Direct Method. Chin. Phys. Lett., 2010, 27(11): 118701-118701.
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2010, Vol. 27 
