摘要Theoretical analyses and Monte Carlo simulation are performed to investigate the detection limit of glucose concentration with near-infrared spectroscopy. The relation between detection limitation of glucose concentration and source--detector separation is derived. Monte Carlo simulation performed with a skin-layered model shows that the ratio of effective photons from the target layer could excess 50% by selecting proper source--detector separation, and that the detection limit of glucose concentration approaches to 0.28mM, which satisfies the requirement of food and drug administration for noninvasive glucose sensing.
Abstract：Theoretical analyses and Monte Carlo simulation are performed to investigate the detection limit of glucose concentration with near-infrared spectroscopy. The relation between detection limitation of glucose concentration and source--detector separation is derived. Monte Carlo simulation performed with a skin-layered model shows that the ratio of effective photons from the target layer could excess 50% by selecting proper source--detector separation, and that the detection limit of glucose concentration approaches to 0.28mM, which satisfies the requirement of food and drug administration for noninvasive glucose sensing.
LUO Yun-Han;HUANG Fu-Rong;LI Shi-Ping;CHEN Zhe. Detection Limit of Glucose Concentration with Near-InfraredAbsorption and Scattering Spectroscopy[J]. 中国物理快报, 2008, 25(3): 1117-1119.
LUO Yun-Han, HUANG Fu-Rong, LI Shi-Ping, CHEN Zhe. Detection Limit of Glucose Concentration with Near-InfraredAbsorption and Scattering Spectroscopy. Chin. Phys. Lett., 2008, 25(3): 1117-1119.
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2008, Vol. 25 
