Translocation of Biopolymer Chain Through a Nanopore: Coil--Helix Transition
GU Fang1, WANG Hai-Jun1,2, HONG Xiao-Zhong3, BA Xin-Wu1
1College of Chemistry and Environment Science, Hebei University, Baoding 0710022International Centre for Materials Physics, Chinese Academy of Sciences, Shenyang 1100163College of Physics Science and Technology, Hebei University, Baoding 071002
Translocation of Biopolymer Chain Through a Nanopore: Coil--Helix Transition
GU Fang1, WANG Hai-Jun1,2, HONG Xiao-Zhong3, BA Xin-Wu1
1College of Chemistry and Environment Science, Hebei University, Baoding 0710022International Centre for Materials Physics, Chinese Academy of Sciences, Shenyang 1100163College of Physics Science and Technology, Hebei University, Baoding 071002
摘要The translocation dynamics of a single biopolymer chain through a nanopore in a membrane is investigated by taking the coil--helix transition into account. Based on the changing of the free energy due to the coil--helix transition, the mean first passage time τ is obtained, and then the corresponding numerical simulations are presented under different conditions. It is shown that the coil--helix transition can significantly shorten the translocation time of the biopolymer chain. In addition, we also discuss the scaling behaviour for τ with the chain length N and some related problems.
Abstract：The translocation dynamics of a single biopolymer chain through a nanopore in a membrane is investigated by taking the coil--helix transition into account. Based on the changing of the free energy due to the coil--helix transition, the mean first passage time τ is obtained, and then the corresponding numerical simulations are presented under different conditions. It is shown that the coil--helix transition can significantly shorten the translocation time of the biopolymer chain. In addition, we also discuss the scaling behaviour for τ with the chain length N and some related problems.
GU Fang;WANG Hai-Jun;HONG Xiao-Zhong;BA Xin-Wu. Translocation of Biopolymer Chain Through a Nanopore: Coil--Helix Transition[J]. 中国物理快报, 2008, 25(8): 2853-5856.
GU Fang, WANG Hai-Jun, HONG Xiao-Zhong, BA Xin-Wu. Translocation of Biopolymer Chain Through a Nanopore: Coil--Helix Transition. Chin. Phys. Lett., 2008, 25(8): 2853-5856.
2008, Vol. 25 
