Dynamical Properties of Potassium Ion Channels with a Hierarchical Model
ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong
School of Sciences, Hebei University of Technology, Tianjin 300130
Dynamical Properties of Potassium Ion Channels with a Hierarchical Model
ZHAN Yong;AN Hai-Long;YU Hui;ZHANG Su-Hua;HAN Ying-Rong
School of Sciences, Hebei University of Technology, Tianjin 300130
关键词 ：
05.10.Gg ,
31.15.Ew ,
87.16.Uv
Abstract ： It is well known that potassium ion channels have higher permeability than K ions, and the permeable rate of a single K ion channel is about 108 ions per second. We develop a hierarchical model of potassium ion channel permeation involving ab initio quantum calculations and Brownian dynamics simulations, which can consistently explain a range of channel dynamics. The results show that the average velocity of K ions, the mean permeable time of K ions and the permeable rate of single channel are about 0.92nm/ns, 4.35ns and 2.30× 108 ions/s, respectively.
Key words ：
05.10.Gg
31.15.Ew
87.16.Uv
出版日期: 2006-11-01
引用本文:
ZHAN Yong;AN Hai-Long;YU Hui;ZHANG Su-Hua;HAN Ying-Rong. Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J]. 中国物理快报, 2006, 23(11): 2906-2908.
链接本文:
https://cpl.iphy.ac.cn/CN/
或
https://cpl.iphy.ac.cn/CN/Y2006/V23/I11/2906
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