Solvent Suppression in Intermolecular Multiple-Quantum Coherence Nuclear Magnetic Resonance Spectra with Only z-axis Gradients
FENG Hai 1,2, ZHANG Sheng-Chun 2, CAI Shu-Hui2, CHEN Zhong2, FENG Ji1
1Institute of Physics, Chinese Academy of Sciences, Beijing 1000802Department of Physics, State Key Laboratory of Physical Chemistry of Solid Surface, Xiamen University, Xiamen 361005
Solvent Suppression in Intermolecular Multiple-Quantum Coherence Nuclear Magnetic Resonance Spectra with Only z-axis Gradients
FENG Hai 1,2;ZHANG Sheng-Chun 2;CAI Shu-Hui2;CHEN Zhong2;FENG Ji1
1Institute of Physics, Chinese Academy of Sciences, Beijing 1000802Department of Physics, State Key Laboratory of Physical Chemistry of Solid Surface, Xiamen University, Xiamen 361005
摘要The solvent peak in the intermolecular multiple-quantum coherence spectra can be suppressed by either applying pulse field gradients or spinning sample along the magic angle direction (ψ=54.7). However, these two methods also suppress the signals of the solute. We design two pulse sequences with only z-axis gradients to suppress the solvent peak without reducing the intensity of solute signals. Compared to the former pulse sequence, the latter pulse sequence is insensitive to the imperfection of pulse flip angles. When the flip angles of the second pulse sequence are purposely deviated 1/10 from the optimal values, the solvent peak is still weak. Theoretical expressions, experimental observations and computer simulations demonstrate that the two methods can be used to effectively suppress solvent peak in intermolecular multiple-quantum coherence spectra.
Abstract：The solvent peak in the intermolecular multiple-quantum coherence spectra can be suppressed by either applying pulse field gradients or spinning sample along the magic angle direction (ψ=54.7). However, these two methods also suppress the signals of the solute. We design two pulse sequences with only z-axis gradients to suppress the solvent peak without reducing the intensity of solute signals. Compared to the former pulse sequence, the latter pulse sequence is insensitive to the imperfection of pulse flip angles. When the flip angles of the second pulse sequence are purposely deviated 1/10 from the optimal values, the solvent peak is still weak. Theoretical expressions, experimental observations and computer simulations demonstrate that the two methods can be used to effectively suppress solvent peak in intermolecular multiple-quantum coherence spectra.
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2007, Vol. 24 
