摘要Based on a deterministic cell cycle model of fission yeast, the effects of the finite cell size on the cell cycle regulation in wee1- cdc25△ double mutant type are numerically studied by using of the chemical Langevin equations. It is found that at a certain region of cell size, our numerical results from the chemical Langevin equations are in good qualitative agreement with the experimental observations. The two resettings to the G2 phase from early stages of mitosis can be induced under the moderate cell size. The quantized cycle times can be observed during such a cell size region. Therefore, a coarse estimation of cell size is obtained from the mesoscopic stochastic cell cycle model.
Abstract：Based on a deterministic cell cycle model of fission yeast, the effects of the finite cell size on the cell cycle regulation in wee1- cdc25△ double mutant type are numerically studied by using of the chemical Langevin equations. It is found that at a certain region of cell size, our numerical results from the chemical Langevin equations are in good qualitative agreement with the experimental observations. The two resettings to the G2 phase from early stages of mitosis can be induced under the moderate cell size. The quantized cycle times can be observed during such a cell size region. Therefore, a coarse estimation of cell size is obtained from the mesoscopic stochastic cell cycle model.
YI Ming;JIA Ya;LIU Quan;ZHU Chun-Lian;YANG Li-Jian. A Coarse Estimation of Cell Size Region from a Mesoscopic Stochastic Cell Cycle Model[J]. 中国物理快报, 2007, 24(7): 1829-1832.
YI Ming, JIA Ya, LIU Quan, ZHU Chun-Lian, YANG Li-Jian. A Coarse Estimation of Cell Size Region from a Mesoscopic Stochastic Cell Cycle Model. Chin. Phys. Lett., 2007, 24(7): 1829-1832.
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