Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors
WANG Hong, DOU Shuo-Xing, WANG Peng-Ye
Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080
Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors
WANG Hong;DOU Shuo-Xing;WANG Peng-Ye
Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080
摘要Kinesin and dynein are two important classes of molecular motors which are responsible for active organelle trafficking and cell division. They can work together to carry a cargo, moving along the microtubule in a coordinated way. We use Monte Carlo method to simulate the dynamics of this coordinated movement. Based on four essential assumptions, our simulations reproduce some features of the recent in vivo experiments. The fast moving speed of the cargo is simulated and the speed distribution is presented.
Abstract：Kinesin and dynein are two important classes of molecular motors which are responsible for active organelle trafficking and cell division. They can work together to carry a cargo, moving along the microtubule in a coordinated way. We use Monte Carlo method to simulate the dynamics of this coordinated movement. Based on four essential assumptions, our simulations reproduce some features of the recent in vivo experiments. The fast moving speed of the cargo is simulated and the speed distribution is presented.
WANG Hong;DOU Shuo-Xing;WANG Peng-Ye. Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors[J]. 中国物理快报, 2008, 25(1): 321-324.
WANG Hong, DOU Shuo-Xing, WANG Peng-Ye. Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors. Chin. Phys. Lett., 2008, 25(1): 321-324.
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