An Intracellular Calcium Oscillation Model and its Property
YING Yang-Jun1, LI Wei-Hua2
1Laboratory of Computation Physics, Institute of Applied Physics and Computational Mathematics, PO Box 8009, Beijing 100088
2Department of Modern Education Technology, Beijing College of Education, Beijing 100035
An Intracellular Calcium Oscillation Model and its Property
YING Yang-Jun1;LI Wei-Hua2
1Laboratory of Computation Physics, Institute of Applied Physics and Computational Mathematics, PO Box 8009, Beijing 100088
2Department of Modern Education Technology, Beijing College of Education, Beijing 100035
Abstract： Intracellular Ca2+ concentration oscillation is one of the typical nonlinear dynamical phenomena in biophysics. According to the experimental facts that when stimulated by different agonists, the cytosolic Ca2+ oscillations of hepatocytes show nearly constant amplitude for two different oscillation-form, simple spikes and complex bursts, we build a new 4-variables model based on the two models proposed by Hoefer [ Biophys J. 77 (1999) 1244] and Kummer et al. [ Biophys. J. 79 (2000) 1188] Our model can simulate both simple-spike and multi-spike-burst oscillations with amplitude of 0.5-0.7μmol/L in a rather wide range of parameters.
YING Yang-Jun;LI Wei-Hua. An Intracellular Calcium Oscillation Model and its Property
[J]. 中国物理快报, 2003, 20(7): 1168-1171.
YING Yang-Jun, LI Wei-Hua. An Intracellular Calcium Oscillation Model and its Property
. Chin. Phys. Lett., 2003, 20(7): 1168-1171.
2003, Vol. 20 
