Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound
LIU Zhen-Bo1,2, FAN Ting-Bo1, GUO Xia-Sheng1, ZHANG Dong1
1Institute of Acoustics, Key Laboratory of Modern Acoustics (Ministry of Education), Nanjing University, Nanjing 210093 2Nanjing Normal University, Nanjing 210097
Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound
LIU Zhen-Bo1,2, FAN Ting-Bo1, GUO Xia-Sheng1, ZHANG Dong1
1Institute of Acoustics, Key Laboratory of Modern Acoustics (Ministry of Education), Nanjing University, Nanjing 210093 2Nanjing Normal University, Nanjing 210097
We study the influence of tissue inhomogeneity on the focused ultrasound based on the phase screen model and the acoustic nonlinear equation. The inhomogeneous tissue is considered as a combination of a homogeneous medium and a phase aberration screen. Six polyethylene (PE) plates with various correlation lengths and standard deviations are made to mimic the inhomogeneity induced by the human body abdominal. Results indicate that the correlation length affects the side lobe structure of the beam pattern; while the standard deviation is associated with the focusing capability. This study provides a theoretical and experimental basis for the development of a precise treatment plan for high intensity focused ultrasound.
We study the influence of tissue inhomogeneity on the focused ultrasound based on the phase screen model and the acoustic nonlinear equation. The inhomogeneous tissue is considered as a combination of a homogeneous medium and a phase aberration screen. Six polyethylene (PE) plates with various correlation lengths and standard deviations are made to mimic the inhomogeneity induced by the human body abdominal. Results indicate that the correlation length affects the side lobe structure of the beam pattern; while the standard deviation is associated with the focusing capability. This study provides a theoretical and experimental basis for the development of a precise treatment plan for high intensity focused ultrasound.
LIU Zhen-Bo;FAN Ting-Bo;GUO Xia-Sheng;ZHANG Dong. Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound[J]. 中国物理快报, 2010, 27(9): 94303-094303.
LIU Zhen-Bo, FAN Ting-Bo, GUO Xia-Sheng, ZHANG Dong. Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound. Chin. Phys. Lett., 2010, 27(9): 94303-094303.
[1] Wu F, Chen W Z, Bai J, Zou J Z, Wang Z L, Zhu H and Wang Z B 2002 Ultrasound Med. Biol. 28 535 [2] Wu F, Wang Z B, Chen W Z, Wang W, Gui Y, Zhang M, Zheng G, Zhou Y, Xu G, Li M, Zhang C, Ye H and Feng R 2004 Ultrason. Sonochem. 11 149 [3] Liu M H, Zhang D and Gong X F 2007 Chin. Phys. Lett. 24 2267 [4] Hallaj I M, Cleveland R O and Hynynen K 2001 J. Acoust. Soc. Am. 109 2245 [5] Zheng X L and Vaezy S 2010 IEEE Trans. Biomed. Eng. 57 71 [6] Liu Z B, Fan T B, Zhang D and Gong X F 2009 Chin. Phys. B 18 4932 [7] Hinkelman L M, Liu D L, Metlay L A and Waag R C 1994 J. Acoust. Soc. Am. 95 530 [8] Huang D H and Tsao J 2002 IEEE Trans. Ultrason. Ferroelect. Freq. Contr. 49 1686 [9] Hinkelman L M, Douglas Mast T and Metlay L A 1998 J. Acoust. Soc. Am. 104 3635 [10] Douglas Mast T, Hinkelman L M, Michael J O and Waag R C 1998 J. Acoust. Soc. Am. 104 3651 [11] Fan T B, Liu Z B, Zhang Z, Zhang D and Gong X F 2009 Chin. Phys. Lett. 26 084302 [12] Tabei M, Douglas Mast T and Waag R C 2003 J. Acoust. Soc. Am. 113 1166