What Governs the Unzipping Process of Double-Stranded DNA
WANG Xiao-Feng1,2, LEI Xiao-Ling1, FANG Hai-Ping1
1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800
2Graduate School of the Chinese Academy of Sciences, Beijing 100049
What Governs the Unzipping Process of Double-Stranded DNA
WANG Xiao-Feng1,2;LEI Xiao-Ling1;FANG Hai-Ping1
1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800
2Graduate School of the Chinese Academy of Sciences, Beijing 100049
Abstract: The unzipping process of double-stranded DNA is analysed using a discrete model at the base level [Chin. Phys. Lett. 22(2005)1540]. The numerical results are consistent with the experimental observations on the force-displacement behaviour including the sequence-dependence. We find that the hydrogen bond interaction in a base pair is crucially important to the force--displacement profile.
WANG Xiao-Feng;LEI Xiao-Ling;FANG Hai-Ping. What Governs the Unzipping Process of Double-Stranded DNA[J]. 中国物理快报, 2006, 23(5): 1339-1342.
WANG Xiao-Feng, LEI Xiao-Ling, FANG Hai-Ping. What Governs the Unzipping Process of Double-Stranded DNA. Chin. Phys. Lett., 2006, 23(5): 1339-1342.