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Dynamical Analysis of Protein Regulatory Network in Budding Yeast Nucleus |
| LI Fang-Ting;JIA Xun |
| School of Physics and Centre for Theoretical Biology, Peking University, Beijing 100871 |
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| Cite this article: |
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LI Fang-Ting, JIA Xun 2006 Chin. Phys. Lett. 23 2307-2310 |
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Abstract Recent progresses in the protein regulatory network of budding yeast Saccharomyces cerevisiae have provided a global picture of its protein network for further dynamical research. We simplify and modularize the protein regulatory networks in yeast nucleus, and study the dynamical properties of the core 37-node network by a Boolean network model, especially the evolution steps and final fixed points. Our simulation results show that the number of fixed points N(k) for a given size of the attraction basin k obeys a power-law distribution N(k) ∝ k-2.024. The yeast network is more similar to a scale-free network than a random network in the above dynamical properties.
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| Keywords:
87.10.+e
87.16.Yc
87.16.Aa
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Published: 01 August 2006
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