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Acoustic Nonlinear Behaviour of Microbubble Contrast Agent |
| YU Jin-Fei1;LU Rong-Rong1;GONG Xiu-Fen1;William T. Shi2 |
| 1State Key Laboratory of Modern Acoustics Institute of Acoustics, Nanjing University, Nanjing 210093
2Department of Radiology and Jefferson Ultrasound Research and Education Institute, Thomas Jefferson University, PA 19107, USA |
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| Cite this article: |
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YU Jin-Fei, LU Rong-Rong, GONG Xiu-Fen et al 2002 Chin. Phys. Lett. 19 1828-1830 |
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Abstract We have investigated the nonlinear characteristics of a microbubble contrast agent SonazoidR (Nycomed, Norway), including the second, third, 1/2-order, 3/2-order and 5/2-order harmonics. We have measured the 1/2-order subharmonic response to different transmit sound pressure. It is found that subharmonic signals can not be generated until the acoustic pressure reached a certain value, which is the most difference subharmonic from high harmonics. This result is favorable for the further study of the subharmonic in the bubbly liquid. The 3/2-order ultraharmoic response to acoustic pressure was also measured.
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| Keywords:
43.25.-x
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Published: 01 December 2002
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