%A Hao Yang, Ke Wang, Hui-Ting Zhang, Jun-Shuai Xie, Guang-Yao Wu, Xin Zhou %T Human Pulmonary Hyperpolarized $^{129}$Xe MRI: a Preliminary Study %0 Journal Article %D 2018 %J Chin. Phys. Lett. %R 10.1088/0256-307X/35/5/058701 %P 058701%V 35 %N 5 %U {https://cpl.iphy.ac.cn/CN/abstract/article_71157.shtml} %8 2018-03-28 %X We study the feasibility and safety of human lung hyperpolarized (HP) $^{129}$Xe magnetic resonance imaging (MRI). There is no significant change in physiological parameters before and after the examinations of all subjects. Compared with computed tomography, HP $^{129}$Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP $^{129}$Xe MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP $^{129}$Xe MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.