| CROSS-DISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY |
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Environmental Impacts on Spiking Properties in Hodgkin-Huxley Neuron with Direct Current Stimulus |
| YUAN Chang-Qing, ZHAO Tong-Jun, ZHAN Yong, ZHANG Su-Hua, LIU Hui, ZHANG Yu-Hong |
| Institute of Biophysics, Hebei University of Technology, Tianjin 300130 |
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| Cite this article: |
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YUAN Chang-Qing, ZHAO Tong-Jun, ZHAN Yong et al 2009 Chin. Phys. Lett. 26 118701 |
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Abstract Based on the well accepted Hodgkin-Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus.
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| Keywords:
87.19.Ll
87.17.Aa
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Received: 05 August 2009
Published: 30 October 2009
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| PACS: |
87.19.ll
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(Models of single neurons and networks)
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87.17.Aa
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(Modeling, computer simulation of cell processes)
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